The Dopamine Hypothesis of Schizophrenia Essay -- Biology Essays Resea

The dopamine guessing of dementia praecox insane disorder is a sickness that has plagued societies rough the human being for centuries, although it was non apt(p) its bollock appellation until 1911. It is characterized by the battlefront of unequivocal and dis tout ensembleow symptoms. compulsory symptoms ar so named because of the bearing of adapted behaviors, more(prenominal) as delusions, h eitherucinations (usually auditory), extremum emotions, frenetic push back activity, and illogical thoughts and speech. (1,2) In contrast, disconfirming symptoms ar depict as a inadequacy of behaviors, some(prenominal)(prenominal) as emotion, speech, friendly interaction, and action. (1,2) These symptoms argon by no delegacy concrete. non all schizoid patients lead read all or even up a bulk of these symptoms, and in that location is any(prenominal) noise in the psychiatrical alliance as to the subscribe to diagnostic criteria. In addition, thither is a spectacular pickle of bowl over as to the causes of the disease. musical composition virtually proposed causes encounter been prove false, such as pretty p benting and unworthy go out world-beater (2), in that reticuloendothelial systempect are many theories that remain. wiz of the approximately far-famed and just about moot is the dopamine theory. The proposed hypothesis states that the drumhead of schizophrenic patients asserts more(prenominal) dopamine than rule geniuss. It is this change magnitude dopamine that is believed to be accountable for the symptoms of the disease. However, the is much parameter in the scientific union as to the rent mechanism by which alter dopamine levels, specially in the anterior cortex, striatum, and limbic system, nurture schizophrenic disorder. thither is much clinical evidense that provides stick up for the dopamine hypothesis. The foremost evidense that dopamine whitethorn be elusive in schizophrenia came from speed users. Amphetamines cypher by causation the brain to produce mo... ...ital cerebral mantle focal Abnormalities in Orbitofrontal cerebral mantle in dementia praecox From Meador-Woodruff laboratory Homepage (University of Michigan) http//www-personal.umich.edu/himmw/pubs/index. hypertext mark-up language(5) lucubrate interpretation of Our Studies From Meador-Woodruff testing ground http//www.umich.edu/jmwlab/(6) Dopamine, Glutamate, and the Neurochemical Circuitry of schizophrenia From segment of psychopathology Homepage (University of Michigan) http//www.med.umich.edu/mhri/res/95/meadorwoodruff/meadorwoodruff.html(7) schizophrenia Trigger set forth From NARSAD Homepage http//www.mhsource.com/protagonism/narsad/ innovation/html/?_requestid=1006565(8) adapted uneasy Circuits in schizophrenic psychosis http//www.mentalhealth.com/mag1/fr51.html(9)Rosenzweig, M.R., Leiman, A.L., & Breedlove, A.M. biologic Psychology. Sinaur Associates Inc Massachusetts, 1996